You would want to create a Frame that has a Location Proximity Condition. Within this frame you should have a Screen Message Resource. This Screen Message Resource should have any amount of responses attached to it. Each response can have an event attached. This event is broadcasted when that response is selected.
Clicking the blue “plus” button on the Screen Message resource and selecting an event will create a frame that will only activate when that event is broadcasted for the Screen Message resource. In this way, you can trigger custom content based on which response is selected.